Farmasötik Kimya Anabilim Dalı
ssaractarhan[at]baskent.edu.tr
0312 246 66 66 2026
• Farmasotik Kimya
Birleşmiş Milletler Sürdürülebilir Kalkınma Amaçları
Yayın Bilgileri
1
Azoles display promising anticonvulsant effects through possible PPAR-alpha activation, NEUROSCIENCE LETTERS, 828(0), 2024
Suat Sari, Sibel Yurtoğlu, Merve Zengin, Monika Marcinkowska, Siwek Agata, Prof. Dr. Selma Saraç Tarhan |
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2
Design, Synthesis, and Molecular Modeling of New and Safe Azole Oxime Esters with Promising Antifungal Activity, ChemistrySelect, 8(18), 2023
Sibel Yurtoğlu, Suat Sarı, Didem Kart, Suna Sabuncuoğlu, Prof. Dr. Selma Saraç Tarhan |
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3
Integrated experimental and theoretical approaches to investigate the molecular mechanisms of the enantioseparation of chiral anticonvulsant and antifungal compounds, Journal of Molecular Structure, 1270(133905), 2022
Prof. Dr. Selma Saraç Tarhan, Nicola Gambocorta, Zeynep Özdemir, İnci Selin Doğan, Fulvio Ciriaco, Yaren Nur Zenni, Arzu Karakurt, Orazio Nicolotti |
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4
Discovery of potent alpha-glucosidase inhibitors through structure based virtual screening of an in-house azole collection, Chemical Biology & Drug Design, 97(3), 2021
Prof. Dr. Selma Saraç Tarhan, Suat Sarı, Burak Barut, Arzu Özel |
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5
Antibacterial azole derivatives: Antibacterial activity, cytotoxicity, and in silico mechanistic studies, DRUG DEVELOPMENT RESEARCH, 81(8), 2020
Prof. Dr. Selma Saraç Tarhan, Suat Sarı, Ahmet Avcı, Ebru Koçak, Didem Kart, Suna Sabuncuoğlu, İnci Selin Doğan, Zeynep Özdemir, İrem Bozbey, Arzu Karakurt, Sevim Dalkara |
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6
Antifungal screening and in silico mechanistic studies of an in-house azole library, Chemical Biology & Drug Design, 94(5), 2019
Prof. Dr. Selma Saraç Tarhan, Suat Sarı, Didem Kart, Suna Sabuncuoğlu, İnci Selin Doğan, Zeynep Özdemir, İrem Bozbey, Melis Gencel, Şebnem Eşsiz, Johannes Reynisson, Arzu Karakurt, Sevim Dalkara |
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7
Discovery of new azoles with potent activity against Candida spp. and Candida albicans biofilms through virtual screening, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 179(0), 2019
Prof. Dr. Selma Saraç Tarhan, Suat Sarı, Didem Kart, Naile Öztürk, F. Betül Kaynak, Melis Gencel, Gülce Taşkor, Arzu Karakurt, Şebnem Eşsiz, Sevim Dalkara |
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8
Synthesis, anticonvulsant activity, and molecular modeling studies of novel 1-phenyl/1-(4-chlorophenyl)-2-(1H-triazol-1-yl)ethanol ester derivatives, MEDICINAL CHEMISTRY RESEARCH, 27(9), 2018
Prof. Dr. Selma Saraç Tarhan, İnci Selin Doğan, Zeynep Özdemir, Suat Sarı, İrem Bozbey, Arzu Karakurt |
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9
New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 130(0), 2017
Prof. Dr. Selma Saraç Tarhan, İnci Selin Doğan, Suat Sarı, Didem Kart, Şebnem Eşsiz Gökhan, İmran Vural, Sevim Dalkara |
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10
New Anti-Seizure (Arylalkyl)azole Derivatives: Synthesis, In Vivo and In Silico Studies, ARCHIV DER PHARMAZIE, 350(6), 2017
Prof. Dr. Selma Saraç Tarhan, Suat Sarı, Sevim Dalkara, Filiz Betül Kaynak, Johannes Reynisson, Arzu Karakurt |
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11
Enantioseparation of some new 1 2 naphthyl 1 ethanol ester derivatives by HPLC on Chiralcel OD, CHROMATOGRAPHIA, 75(19), 2012
Prof. Dr. Selma Saraç Tarhan, A. Karakurt, S. Dalkara |
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12
Synthesis and antimicrobial activity of some 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives, Turkish Journal Of Medical Sciences, 8(2), 2011
Prof. Dr. Selma Saraç Tarhan, Evren Sağlam, Ekrem Kılıç, Meral Özalp, Mevlüt Ertan |
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13
Studies on synthesis and biological activitiy of 6-ethyl-4-aryl-5-methoxycarbonyl-3,4-dihydropyrimidin-2(1H)-ones, ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 57(3), 2007
Prof. Dr. Selma Saraç Tarhan, Murat Çiftçi, İnci Selin Zorkun, Özgül Tunç, Kevser Erol |
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14
Synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-thione derivatives as potential calcium channel blockers, BIOORGANIC & MEDICINAL CHEMISTRY, 14(24), 2006
Prof. Dr. Selma Saraç Tarhan, İnci Selin Zorkun, Semra Çelebi, Kevser Erol |
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15
Synthesis and in vitro calcium antagonist activity of 4-aryl-7,7-dimethyl/1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione derivatives, Farmaco, 58(0), 2003
Prof. Dr. Selma Saraç Tarhan, Mine Yarım, F. Sultan Kılıç, Kevser Erol |
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16
Studies on new 2-thioxo-1,2,3,4-tetrahydropyrimidines and their condensed derivatives, Fabad Journal of Pharmaceutical Sciences, 27(2), 2002
Prof. Dr. Selma Saraç Tarhan, Mine Yarım, Birsen Tozkoparan, Mevlüt Ertan, Berrin Özçelik, Ufuk Abbasoğlu |
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17
Synthesis, enantioseparation and pharmacological activity of 4-aryl-7,7-dimethyl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones, ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 52(0), 2002
Prof. Dr. Selma Saraç Tarhan, Mine Yarım, Mevlüt Ertan, F. Sultan Kılıç, Kevser Erol |
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18
Separation of the enantiomers of 4-aryl-7,7-dimethyl- and 1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones by chiral HPLC, CHROMATOGRAPHIA, 56(0), 2002
Prof. Dr. Selma Saraç Tarhan, M. Yarım |
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19
4-Aryl-6,6-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones: Synthesis, chromatographic resolution and pharmacological activity, PHARMAZIE, 56(0), 2001
Prof. Dr. Selma Saraç Tarhan, M. Yarım, M. Ertan, F.S. Kılıç, K. Erol |
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20
Crystal structure of 1,7,7-trimethyl-4-(4-methylphenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione, ANALYTICAL SCIENCES, 17(0), 2001
Prof. Dr. Selma Saraç Tarhan, M. Murat Candan, Engin Kendi, Mine Yarım, Mevlüt Ertan |
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21
Crystal structure of 4-(4-bromophenyl)-1,7,7-trimethyl-1,2,3,4,5,6,7,8- octahydroquinazolin-2,5-dione, ANALYTICAL SCIENCES, 17(8), 2001
Prof. Dr. Selma Saraç Tarhan, M. Murat Candan, Engin Kendi, Mine Yarım, Mevlüt Ertan, M. Murat Candan, Engin Kendi, Mine Yarım, Mevlüt Ertan |
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22
Separation of enantiomers of some condensed dihydropyrimidine derivatives by HPLC using chiral stationary phases, Fabad Journal of Pharmaceutical Sciences, 25(4), 2000
Prof. Dr. Selma Saraç Tarhan, Birsen Tozkoparan, Mevlüt Ertan |
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23
Enantioseparation of 3,4-dihydroxyphenylalanine and 2-hydrazino-2-methyl-3-(3,4-dihydroxyphenyl)-propanoic acid by capillary electrophoresis using cyclodextrins, JOURNAL OF CHROMATOGRAPHY A, 875(0), 2000
Prof. Dr. Selma Saraç Tarhan, Bezhan Chankvetadze, Gottfried Blaschke |
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24
Separation of levodopa carbidopa and their related impurities by capillary electrophoresis, Fabad Journal of Pharmaceutical Sciences, 25(3), 2000
Prof. Dr. Selma Saraç Tarhan |
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25
Synthesis, structural elucidation and pharmacological properties of some 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H)-pyrimidinones, FARMACO, 54(0), 1999
Prof. Dr. Selma Saraç Tarhan, M. Yarım, M. Ertan, Ö (Sarnıç) Batu, K. Erol |
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26
Analytical resolution of 4-aryl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones using a cellulose chiral stationary phase, ANALYTICAL LETTERS, 32(6), 1999
Prof. Dr. Selma Saraç Tarhan, Mine Yarım, Mevlüt Ertan |
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27
Synthesis, chemical and pharmacological properties of some 4-aryl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones, PHARMAZIE, 53(2), 1998
Prof. Dr. Selma Saraç Tarhan, M. Yarım, M. Ertan, S. Boydağ, K. Erol |
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28
4-Aryl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thione derivatives: Synthesis, enantiomeric separation and in vitro screening as calcium antagonists, Bollettino Chimico Farmaceutico, 136(11), 1997
Prof. Dr. Selma Saraç Tarhan, M. Yarım, M. Ertan, K. Erol, Y. Aktan |
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29
4-(2-Methylphenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione (I) and 4-(4-chlorophenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione (II), CRYSTAL RESEARCH AND TECHNOLOGY, 32(6), 1997
Prof. Dr. Selma Saraç Tarhan, E. Kendi, M. Yarım, M. Ertan, M. Läge, B. Krebs |
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30
3,4-Dihydro-2H-1,3-benzoxazine derivatives and their antimicrobial activities, Turkish Journal of Medical Sciences, 18(0), 1993
Prof. Dr. Selma Saraç Tarhan |
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31
Studies on some 10-[2-(N,N-disubstituted thiocarbamoylthio)acetyl]phenothiazine derivatives, ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 42(0), 1992
Prof. Dr. Selma Saraç Tarhan, E. Palaska, C. Şafak, H. Erdoğan, K. Erol, R.S. Alpan |
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32
Synthesis and calcium antagonistic activity of some new 2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives, ARCHIV DER PHARMAZIE, 324(0), 1991
Prof. Dr. Selma Saraç Tarhan, Mevlüt Ertan, Ayla Balkan, Serdar Uma, Jean Francois Renaud, Yves Rollad |
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33
Synthesis and antimicrobial activities of some new tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives of cefadroxil, ARCHIV DER PHARMAZIE, 324(0), 1991
Prof. Dr. Selma Saraç Tarhan, Mevlüt Ertan, Ayla Balkan, Nuran Yulug |
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34
Synthesis, and biological evaluations of some 2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives, ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 41(0), 1991
Prof. Dr. Selma Saraç Tarhan, M. Ertan, A. Balkan, S. Uma, K. Rübseman, J.F. Renaud |
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35
Synthesis and antimicrobial activities of some new tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives of cephalexin, ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 40(0), 1990
Prof. Dr. Selma Saraç Tarhan, A. Balkan, M. Ertan, N. Yuluğ |
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36
Synthesis and antimicrobial activities of some new tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives of amoxicillin, ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 40(0), 1990
Prof. Dr. Selma Saraç Tarhan, M. Ertan, N. Yuluğ |
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37
Synthesis of some 1-acetyl-3,5-diaryl-2-pyrazoline derivatives and their antimicrobial activities, JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 67(0), 1990
Prof. Dr. Selma Saraç Tarhan, C. Şafak, A. Tayhan, N. Yulug |
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38
Antifungal activities of some 1,3,5-triphenyl-2-pyrazoline derivatives against molds, Acta Pharmaceutica Turcica, 31(0), 1989
Prof. Dr. Selma Saraç Tarhan, N. Yuluğ, A.A. Bilgin, A. Tayhan |
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39
Bazı 1-asetil-3,5-difenil-2-pirazolin türevleri üzerinde çalışmalar-II. Küfler üzerindeki antifungal etkileri, Fabad Journal of Pharmaceutical Sciences, 9(2), 1989
Prof. Dr. Selma Saraç Tarhan, N. Yuluğ, A.A. Bilgin, A. Tayhan |
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40
Bazı hidroksişalkonların sentezi ve maya benzeri funguslara karşı aktivitelerinin incelenmesi, HACETTEPE ÜNİVERSİTESİ ECZACILIK FAKÜLTESİ DERGİSİ, 1(1), 1987
Prof. Dr. Selma Saraç Tarhan, N. Yuluğ, A. Tayhan, D. Berkman |
Editör Bilgileri |
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1
İlaç: Tasarım, Sentez ve Analiz Yöntemleri, İlk Baskı, Ankara Nobel Tıp Kitabevleri Ltd. Şti., 2024
M. Abdullah Alagöz, S. Ebru Büyüktuncel, İnci Selin Doğan, Arzu Kararkurt, Zeynep Özdemir, Naile Öztürk, Prof. Dr. Selma Saraç Tarhan, Keriman Sarı Özadalı, Suat Sarı, Ebru Savan |
Kitap Bölümü Bilgileri |
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2
Kolon Kromatografisi, In:İlaç: Tasarım, Sentez ve Analiz Yöntemleri, 299-306, 2024
Prof. Dr. Selma Saraç Tarhan |
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3
İnce Tabaka Kromatografisi, In:İlaç: Tasarım, Sentez ve Analiz Yöntemleri, 279-298, 2024
Prof. Dr. Selma Saraç Tarhan |
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4
Kromatografide Özel Uygulamalar, In:İlaç: Tasarım, Sentez ve Analiz Yöntemleri, 357-368, 2024
Prof. Dr. Selma Saraç Tarhan |
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5
Kromatografik Yöntemler, In:İlaç: Tasarım, Sentez ve Analiz Yöntemleri, 261-277, 2024
Prof. Dr. Selma Saraç Tarhan |
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1
2nd Istanbul International Inventions Fair (ISIF 2017) Uluslararası Buluş Fuarı, , Bronz Madalya, 03.02.2017 Bilim Sanayi ve Teknoloji Bakanlığı |
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2
2005-2006 yılları Novartis Farmasötik ve Medisinal Kimya İlaç Tasarım ve Geliştirme Araştırma İkincilik Ödülü, 14.04.2007 Novartis İlaç Firması |
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1-fenil-2-(1H-imidazol-1-il) etanon oksim esterlerinin sentezi ve biyolojik etkileri üzerinde çalışmalar Yüksek Lisans 2020 |
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1-fenil/1-(4-klorofenil)-2-(1h-imidazol-1-il)etanol esterlerinin sentezi ve biyolojik etkileri üzerinde çalışmalar Uzmanlık 2012 |
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4-aril-3,4-dihidropirimidin-2(1H)-tiyon türevleri üzerine çalışmalar Yüksek Lisans 2005 |
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Bazı tetrahidropirimidin türevlerinin sentezleri ve biyolojik etkileri üzerinde çalışmalar Yüksek Lisans 2004 |
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Biyolojik etkili bazı oktahidrokinazolin türevlerinin sentezi, yapı analizi ve enansiyomer ayırımı Uzmanlık 2000 |
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Bazı oktahidrokinazolin türevleri üzerinde çalışmalar Yüksek Lisans 1995 |
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FARMASÖTİK KİMYA III |
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LABORATUVAR GÜVENLİĞİ |
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FARMASÖTİK KİMYA UYGULAMALARI II |
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İLAÇ ETKEN MADDESİ TASARIMI |
BAŞKENT ÜNİVERSİTESİ